FWD: Medicinenet-What is Enbrel?
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FWD: Medicinenet-What is Enbrel?
byrd45 Fri Jan 09, 2009 12:57 am
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From: byrd45 (Original Message) Sent: 8/9/2006 9:47 AM
WHAT IS ENBREL?
A lot of people are asking about the drug ENBREL again. Here is what MedicineNet says about it;
GENERIC NAME: etanercept
BRAND NAME: Enbrel - DRUG CLASS AND MECHANISM: Etanercept is an injectable drug that blocks tumor necrosis factor alpha (TNF alpha) and is used for treating rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis. TNF alpha is a protein that the body produces during the inflammatory response, the body's reaction to injury. TNF alpha promotes the inflammation and its associated fever and signs (pain, tenderness, and swelling) in several inflammatory conditions including rheumatoid arthritis and ankylosing spondylitis. Etanercept is a synthetic (man-made) protein that binds to TNF alpha. It thereby acts like a sponge to remove most of the TNF alpha molecules from the joints and blood. This prevents TNF alpha from promoting inflammation and the fever, pain, tenderness and swelling of joints in patients with rheumatoid or psoriatic arthritis and ankylosing spondylitis. Etanercept reduces the signs and symptoms of rheumatoid arthritis, the arthritis of psoriasis, and ankylosing spondylitis. It prevents the progressive destruction of the joints in patients with rheumatoid arthritis and the arthritis of psoriasis.
PRESCRIBED FOR: Etanercept is used as primary treatment to reduce the pain, swelling and tenderness of joints resulting from moderate to severe rheumatoid arthritis in adults. It also may be used when rheumatoid arthritis has not adequately responded to other drugs (called disease-modifying medicines for rheumatoid arthritis). Etanercept can be used in combination with methotrexate in patients who do not respond adequately to methotrexate alone.
Etanercept also is used to reduce the signs and symptoms of moderately to severely active, polyarticular-course, juvenile rheumatoid arthritis in patients who have had an inadequate response to one or more disease-modifying medicines.
Etanercept is approved for the treatment of ankylosing spondylitis and the arthritis of psoriasis. It can prevent the progressive destruction of the joints in patients with psoriatic arthritis. Etanercept can improve physical function in patients with psoriatic arthritis. It also is reported to be of benefit in psoriasis, and uveitis.
Etanercept is not recommended for persons with preexisting disease of the central nervous system (brain and/or spinal cord) or for those with multiple sclerosis, myelitis, or optic neuritis.
http://www.medicinenet.com/etanercept/article.htm
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Recommend Delete Message 1 of 1 in Discussion
From: byrd45 (Original Message) Sent: 8/9/2006 9:47 AM
WHAT IS ENBREL?
A lot of people are asking about the drug ENBREL again. Here is what MedicineNet says about it;
GENERIC NAME: etanercept
BRAND NAME: Enbrel - DRUG CLASS AND MECHANISM: Etanercept is an injectable drug that blocks tumor necrosis factor alpha (TNF alpha) and is used for treating rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis. TNF alpha is a protein that the body produces during the inflammatory response, the body's reaction to injury. TNF alpha promotes the inflammation and its associated fever and signs (pain, tenderness, and swelling) in several inflammatory conditions including rheumatoid arthritis and ankylosing spondylitis. Etanercept is a synthetic (man-made) protein that binds to TNF alpha. It thereby acts like a sponge to remove most of the TNF alpha molecules from the joints and blood. This prevents TNF alpha from promoting inflammation and the fever, pain, tenderness and swelling of joints in patients with rheumatoid or psoriatic arthritis and ankylosing spondylitis. Etanercept reduces the signs and symptoms of rheumatoid arthritis, the arthritis of psoriasis, and ankylosing spondylitis. It prevents the progressive destruction of the joints in patients with rheumatoid arthritis and the arthritis of psoriasis.
PRESCRIBED FOR: Etanercept is used as primary treatment to reduce the pain, swelling and tenderness of joints resulting from moderate to severe rheumatoid arthritis in adults. It also may be used when rheumatoid arthritis has not adequately responded to other drugs (called disease-modifying medicines for rheumatoid arthritis). Etanercept can be used in combination with methotrexate in patients who do not respond adequately to methotrexate alone.
Etanercept also is used to reduce the signs and symptoms of moderately to severely active, polyarticular-course, juvenile rheumatoid arthritis in patients who have had an inadequate response to one or more disease-modifying medicines.
Etanercept is approved for the treatment of ankylosing spondylitis and the arthritis of psoriasis. It can prevent the progressive destruction of the joints in patients with psoriatic arthritis. Etanercept can improve physical function in patients with psoriatic arthritis. It also is reported to be of benefit in psoriasis, and uveitis.
Etanercept is not recommended for persons with preexisting disease of the central nervous system (brain and/or spinal cord) or for those with multiple sclerosis, myelitis, or optic neuritis.
http://www.medicinenet.com/etanercept/article.htm
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